Jeff K. J. Cheng

Welcome to my semi-professional website.

Learn about myself, my research and other interests.


Anchor:AboutMe

About Me

I am currently a PhD student studying at the School of Life Sciences at the University of Warwick with Dr Meera Unnikrishnan. My research revolves around the nosocomial pathogen Clostridioides difficile and its interactions with the human gut, specifically adherence and colonization. I also delved further into its capabilities in stress response and persistence.
That being said, I am interested in all things microbiology and keen to learn as much as possible. I love working in the lab, trying new things every other week, debugging and coming up with wacky ideas. Feel free to contact me via email or Twitter (see below).

Anchor:Research-Interests

Research Interests

Current Projects

  • Elucidation of Clostridioides difficile proteins involved with host-pathogen colonization at the University of Warwick with the Unnikrishnan Lab.
  • Uncovering the σB stress response mechanism in Clostridioides difficile at the University of Warwick with the Unnikrishnan Lab.

Previous Projects

  • COG UK Consortium. A nationwide project carrying out whole-genome sequencing of SARS-CoV-2 (COVID-19) isolates with the aim of monitoring transmission and identifying variants. My role in this project involved library preparation and sequencing of inactivated clinical samples at the University Hospital of Coventry and Warwickshire.
  • Determining the efficacy of bacteriophage cocktails for treatment of Clostridioides difficile using Galleria mellonella as an infection model, at the University of Leicester with Professor Martha Clokie.
  • Workshop Co-ordinator and Technician for the Second East African Phage Workshop at Pwani University, Kenya, with Phages for Global Health.


Anchor:Publications

Publications

  • 2021

    Hassall, J., Cheng K. J. J., Unnikrishnan, M. Dissecting Individual Interactions between Pathogens and Commensal Bacteria within a Multispecies Gut Microbial Community. mSphere, 6, e00013-21. DOI:10.1128/mSphere.00013-21

  • 2020

    Frost, L., Cheng K. J. J., Unnikrishnan, M. Clostridioides difficile biofilms: A mechanism of persistence in the gut? PLOSPathogens, 17(3): e1009348. DOI: 10.1371/journal.ppat.1009348

    Nale, Y. J., Chutia, M., Cheng K. J. J., Clokie, R. J. M. Refining the Galleria mellonella Model by Using Stress Markers Genes to Assess Clostridioides difficile Infection and Recuperation during Phage Therapy. Microorganisms, 8(9), 1306. DOI: 10.3390/microorganisms8091306


Anchor:Contact-Me

Contact Details

Address

Jeffrey (Jeff) Cheng

School of Life Sciences

Gibbet Hill

University of Warwick

Coventry

CV4 7AL

Email

Work: J.Cheng.7@warwick.ac.uk

Personal: Jeff.K.J.Cheng@gmail.com

Social Media


Anchor:News

News

This is just a place for my updates, press releases, ramblings, interesting tidbits and all things odds and ends.